C3 Rabbit pAb, Polyclonal
Artikelnummer:
ABB-A16781
- Bilder (1)
| Artikelname: | C3 Rabbit pAb, Polyclonal |
| Artikelnummer: | ABB-A16781 |
| Hersteller Artikelnummer: | A16781 |
| Alternativnummer: | ABB-A16781-20UL,ABB-A16781-100UL,ABB-A16781-1000UL,ABB-A16781-500UL |
| Hersteller: | ABclonal |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | ELISA, WB |
| Spezies Reaktivität: | Mouse |
| Immunogen: | Synthetic peptide. This information is considered to be commercially sensitive. |
| Alternative Synonym: | ASP, Plp, HSE-MSF, C3 |
| This gene encodes complement protein C3 which plays a central role in the classical, alternative and lectin activation pathways of the complement system. The encoded preproprotein undergoes a multi-step processing to generate various functional peptides. Mice deficient in the encoded protein fail to clear bacteria from the blood stream upon infection, display diminished airway hyperresponsiveness and lung eosinophilia upon allergen-induced pulmonary allergy, and develop severe lung injury after deposition of IgG immune complexes. Deficiency of the homolog of the encoded protein in humans was found to be associated with increased susceptibility to infections, age-related macular degeneration, and atypical hemolytic uremic syndrome. |
| Application Verdünnung: | WB,1:500 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. |
| Anwendungsbeschreibung: | Cross-Reactivity: Mouse,Rat. ResearchArea: Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway. Shipping: Ice Bag |
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Western blot analysis of lysates from Rat lung, using C3 Rabbit pAb (A16781) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 180s. |
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