CLCN1 Rabbit mAb, Unconjugated, Monoclonal
Artikelnummer:
ABB-A21237
- Bilder (1)
| Artikelname: | CLCN1 Rabbit mAb, Unconjugated, Monoclonal |
| Artikelnummer: | ABB-A21237 |
| Hersteller Artikelnummer: | A21237 |
| Alternativnummer: | ABB-A21237-100UL,ABB-A21237-20UL |
| Hersteller: | ABclonal |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | ELISA, WB |
| Spezies Reaktivität: | Human |
| Immunogen: | Synthetic peptide. This information is considered to be commercially sensitive. |
| Konjugation: | Unconjugated |
| Alternative Synonym: | CLC1, CLCN1 |
| The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. The protein encoded by this gene regulates the electric excitability of the skeletal muscle membrane. Mutations in this gene cause two forms of inherited human muscle disorders: recessive generalized myotonia congenita (Becker) and dominant myotonia (Thomsen). Alternative splicing results in multiple transcript variants. |
| Application Verdünnung: | WB,1:2000 - 1:5000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. |
| Anwendungsbeschreibung: | Cross-Reactivity: Human. ResearchArea: Signal Transduction,Endocrine Metabolism,Neuroscience. Shipping: Ice Bag |
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Western blot analysis of lysates from wild type (WT) and 293T cells transfected with CLCN1 (Human) using CLCN1 Rabbit mAb (A21237) at 1:5000 dilution incubated overnight at 4°C. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 20 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020) .Exposure time: 45 s. |
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