Epac1/RAPGEF3 Rabbit pAb, Unconjugated, Polyclonal

Artikelnummer: ABB-A2199
Artikelname: Epac1/RAPGEF3 Rabbit pAb, Unconjugated, Polyclonal
Artikelnummer: ABB-A2199
Hersteller Artikelnummer: A2199
Alternativnummer: ABB-A2199-20UL,ABB-A2199-100UL,ABB-A2199-500UL,ABB-A2199-1000UL
Hersteller: ABclonal
Wirt: Rabbit
Kategorie: Antikörper
Applikation: ELISA, WB
Spezies Reaktivität: Human
Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Konjugation: Unconjugated
Alternative Synonym: EPAC, EPAC1, bcm910, HSU79275, CAMP-GEFI, Epac1/RAPGEF3
Enables guanyl-nucleotide exchange factor activity and protein domain specific binding activity. Involved in several processes, including positive regulation of protein modification process, regulation of actin cytoskeleton organization, and regulation of syncytium formation by plasma membrane fusion. Located in filopodium, lamellipodium, and microvillus. Colocalizes with cortical actin cytoskeleton and plasma membrane. Biomarker of congestive heart failure.
Klonalität: Polyclonal
Molekulargewicht: 104kDa
NCBI: 10411
UniProt: O95398
Reinheit: Affinity purification
Sequenz: MVLRRMHRPRSCSYQLLLEHQRPSCIQGLRWTPLTNSEESLDFSESLEQASTERVLRAGRQLHRHLLATCPNLIRDRKYHLRLYRQCCSGRELVDGILALGLGVHSRSQVVGICQVLLDEGALCHVKHDWAFQDRDAQFYRFPGPEPEPVGTHEMEEELAEAVALLSQRGPDALLTVALRKPPGQRTDEELDLIFEELLH
Target-Kategorie: RAPGEF3
Antibody Type: Primary Antibody
Application Verdünnung: WB,1:500 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
Anwendungsbeschreibung: Cross-Reactivity: Human,Mouse. ResearchArea: Signal Transduction,G protein signaling,G-Protein-Coupled Receptors Signaling to MAPK Erk,MAPK-Erk Signaling Pathway,Endocrine Metabolism,Immunology Inflammation. Shipping: Ice Bag
Western blot analysis of various lysates using Epac1/RAPGEF3 Rabbit pAb (A2199) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.