ABflo 647 Rabbit anti-Human Cytokeratin 19/KRT19 mAb, Monoclonal

Artikelnummer: ABB-A22066
Artikelname: ABflo 647 Rabbit anti-Human Cytokeratin 19/KRT19 mAb, Monoclonal
Artikelnummer: ABB-A22066
Hersteller Artikelnummer: A22066
Alternativnummer: ABB-A22066-2X100T,ABB-A22066-100T,ABB-A22066-5X100T
Hersteller: ABclonal
Wirt: Rabbit
Kategorie: Antikörper
Applikation: FC
Spezies Reaktivität: Human
Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
Konjugation: ABflo 647
Alternative Synonym: K19, CK19, K1CS
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21.
Klonalität: Monoclonal
Konzentration: FC (intra)
Molekulargewicht: 44kDa
NCBI: 3880
UniProt: P08727
Reinheit: Affinity purification
Target-Kategorie: KRT19
Application Verdünnung: FC (intra),5 µl per 10 6 cells in 100 µl volume
Anwendungsbeschreibung: Cross-Reactivity: Human. ResearchArea: Signal Transduction,Cell Biology Developmental Biology,Cytoskeleton,Intermediate Filaments,Extracellular Matrix,Keratin,Stem Cells. Shipping: Ice Bag
Flow cytometry:1X10 6 Jurkat cells (negative control,left)and MCF7 cells (right) were intracellularly-stained with ABflo 647 Rabbit anti-Human Cytokeratin 19 (KRT19) mAb(A22066,5 µl/Test,orange line) or ABflo 647 Rabbit IgG isotype control (A22070,5 µl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line).