TGF beta Receptor I (TGFBR1) Rabbit mAb, Monoclonal
Artikelnummer:
ABB-A22151
- Bilder (1)
| Artikelname: | TGF beta Receptor I (TGFBR1) Rabbit mAb, Monoclonal |
| Artikelnummer: | ABB-A22151 |
| Hersteller Artikelnummer: | A22151 |
| Alternativnummer: | ABB-A22151-100UL,ABB-A22151-20UL |
| Hersteller: | ABclonal |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | ELISA, WB |
| Spezies Reaktivität: | Human |
| Immunogen: | Synthetic peptide. This information is considered to be commercially sensitive. |
| Alternative Synonym: | AAT5, ALK5, ESS1, LDS1, MSSE, SKR4, TBRI, ALK-5, LDS1A, LDS2A, TBR-i, TGFR-1, ACVRLK4, tbetaR-I, TGF beta Receptor I (TGFBR1) |
| The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. |
| Application Verdünnung: | WB,1:2000 - 1:8000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. |
| Anwendungsbeschreibung: | Cross-Reactivity: Human. ResearchArea: Cancer,Signal Transduction,Cell Biology Developmental Biology,Growth factors,TGF-b-Smad Signaling Pathway,Endocrine Metabolism,Stem Cells,Cardiovascular,Angiogenesis,Hypoxia. Shipping: Ice Bag |
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Western blot analysis of lysates from SK-BR-3 cells using TGF beta Receptor I (TGFBR1) Rabbit mAb (A22151) at 1:5000 dilution incubated at room temperature for 1.5 hours. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90 s. |
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