MAPKAPK-2/MK2 Rabbit mAb, Unconjugated, Monoclonal

Artikelnummer: ABB-A22183
Artikelname: MAPKAPK-2/MK2 Rabbit mAb, Unconjugated, Monoclonal
Artikelnummer: ABB-A22183
Hersteller Artikelnummer: A22183
Alternativnummer: ABB-A22183-100UL,ABB-A22183-20UL
Hersteller: ABclonal
Wirt: Rabbit
Kategorie: Antikörper
Applikation: ELISA, WB
Spezies Reaktivität: Human
Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
Konjugation: Unconjugated
Alternative Synonym: MK2, MK-2, MAPKAP-K2, MAPKAPK-2/MK2
This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene.
Klonalität: Monoclonal
Molekulargewicht: 46kDa
NCBI: 9261
UniProt: P49137
Reinheit: Affinity purification
Target-Kategorie: MAPKAPK2
Application Verdünnung: WB,1:1000 - 1:5000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
Anwendungsbeschreibung: Cross-Reactivity: Human,Mouse,Rat. ResearchArea: Protein phosphorylation,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors Signaling to MAPK Erk,Kinase,Serine threonine kinases,Cell Biology Developmental Biology,Cytoskeleton,Microfilaments,Microtubules,Endocrine Metabolism,Lipid Metabolism,Immunology Inflammation,Cardiovascular,Blood. Shipping: Ice Bag
Western blot analysis of various lysates, using MAPKAPK-2/MK2 Rabbit mAb (A22183) at1:2000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 30s.