LRP5 Rabbit mAb, Unconjugated, Monoclonal
Artikelnummer:
ABB-A22327
- Bilder (1)
| Artikelname: | LRP5 Rabbit mAb, Unconjugated, Monoclonal |
| Artikelnummer: | ABB-A22327 |
| Hersteller Artikelnummer: | A22327 |
| Alternativnummer: | ABB-A22327-100UL,ABB-A22327-20UL |
| Hersteller: | ABclonal |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | ELISA, WB |
| Spezies Reaktivität: | Human |
| Immunogen: | Synthetic peptide. This information is considered to be commercially sensitive. |
| Konjugation: | Unconjugated |
| Alternative Synonym: | HBM, LR3, OPS, EVR1, EVR4, LRP7, OPPG, BMND1, LRP-5, LRP-7, OPTA1, PCLD4, VBCH2, LRP5 |
| This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. Alternative splicing results in multiple transcript variants. |
| Application Verdünnung: | WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. |
| Anwendungsbeschreibung: | Cross-Reactivity: Human,Mouse. ResearchArea: Epigenetics Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Cancer,Signal Transduction,mTOR Signaling Pathway,Cell Biology Developmental Biology,Cytoskeleton,Microtubules,Extracellular Matrix,Bone,Wnt -Catenin Signaling Pathway,ESC Pluripotency and Differentiation,Endocrine Metabolism,Lipid Metabolism,Cholesterol Metabolism,Neuroscience,Stem Cells,Cardiovascular,Lipids. Shipping: Ice Bag |
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Western blot analysis of various lysates, using LRP5 Rabbit mAb (A22327) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 180s. |
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