Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Konjugation:
ABflo 488
Alternative Synonym:
CD215
This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.
Cross-Reactivity: Human. ResearchArea: Signal Transduction,Cell Biology Developmental Biology,Apoptosis,Endocrine Metabolism,Endocrine and metabolic diseases,Obesity,Immunology Inflammation,CDs. Shipping: Ice Bag
Flow cytometry:1X10 6 293Fcells (negative control,left)and 293F(Transfection,right) cells were surface-stained with ABflo 488 Rabbit anti-Human CD215/IL-15R mAb(A22582,5 µl/Test,orange line) or ABflo 488 Rabbit IgG isotype control (A22069,5 µl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line).
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