ABflo 488 Rabbit anti-Human IL-17RB mAb, Monoclonal

Artikelnummer: ABB-A24315
Artikelname: ABflo 488 Rabbit anti-Human IL-17RB mAb, Monoclonal
Artikelnummer: ABB-A24315
Hersteller Artikelnummer: A24315
Alternativnummer: ABB-A24315-100T,ABB-A24315-2X100T,ABB-A24315-5X100T
Hersteller: ABclonal
Wirt: Rabbit
Kategorie: Antikörper
Applikation: FC
Spezies Reaktivität: Human
Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Konjugation: ABflo 488
Alternative Synonym: IL17RB, CRL4, EVI27, IL17BR, IL17RH1, interleukin-17 receptor B
The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor.
Klonalität: Monoclonal
Konzentration: FC
Molekulargewicht: 31kDa/55kDa
NCBI: 55540
UniProt: Q9NRM6
Reinheit: Affinity purification
Target-Kategorie: IL17RB
Application Verdünnung: FC,5 µl per 10 6 cells in 100 µl volume
Anwendungsbeschreibung: Cross-Reactivity: Human. ResearchArea: Cancer,Cell Biology & Developmental Biology,Cell Cycle,Cell differentiation,Immunology & Inflammation,Cytokines,Interleukins,Cell Intrinsic Innate Immunity Signaling Pathway. Shipping: Ice Bag
Flow cytometry:1X10 6 MOLT-4 cells (negative control,Left)and HepG2 cells (Right) were surface-stained with ABflo 488 Rabbit anti-Human IL-17RB mAb(A24315,5 µl/Test,orange line) or ABflo 488 Rabbit IgG isotype control (A22069,5 µl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line).