CD324/E-Cadherin Rabbit pAb, Unconjugated, Polyclonal
Artikelnummer:
ABB-A24874
- Bilder (1)
| Artikelname: | CD324/E-Cadherin Rabbit pAb, Unconjugated, Polyclonal |
| Artikelnummer: | ABB-A24874 |
| Hersteller Artikelnummer: | A24874 |
| Alternativnummer: | ABB-A24874-100UL,ABB-A24874-20UL,ABB-A24874-1000UL,ABB-A24874-500UL |
| Hersteller: | ABclonal |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | ELISA, WB |
| Spezies Reaktivität: | Mouse |
| Immunogen: | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
| Konjugation: | Unconjugated |
| Alternative Synonym: | CDH1, Arc-1, CD324, CDHE, ECAD, LCAM, UVO, AA960649, ARC-1, E-cad, Ecad, L-CAM, Um, cadherin-1, CD324/E-Cadherin |
| This gene encodes E-cadherin, a calcium-dependent cell adhesion molecule that functions in the establishment and maintenance of epithelial cell morphology during embryongenesis and adulthood. The encoded preproprotein undergoes proteolytic processing to generate a mature protein. Targeted mutations disrupting binding of calcium to the encoded protein in mice cause death in utero due to failed blastocyst and trophectoderm formation. This gene is located adjacent to a related cadherin gene on chromosome 8. |
| Klonalität: | Polyclonal |
| Molekulargewicht: | 98kDa |
| NCBI: | 12550 |
| UniProt: | P09803 |
| Reinheit: | Affinity purification |
| Sequenz: | WVIPPISCPENEKGEFPKNLVQIKSNRDKETKVFYSITGQGADKPPVGVFIIERETGWLKVTQPLDREAIAKYILYSHAVSSNGEAVEDPMEIVITVTDQNDNRPEFTQEVFEGSVAEGAVPGTSVMKVSATDADDDVNTYNAAIAYTIVSQDPELPHKNMFTVNRDTGVISVLTSGLDRESYPTYTLVVQAADLQGEGLSTTAKAVITVKD |
| Target-Kategorie: | Cdh1 |
| Antibody Type: | Primary Antibody |
| Application Verdünnung: | WB,1:1000 - 1:5000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. |
| Anwendungsbeschreibung: | Cross-Reactivity: Human,Mouse. ResearchArea: Cancer,Invasion and Metastasis,Signal Transduction,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Centrosome,Cell Adhesion,Cadherins,Tight Junctions,Cytoskeleton,Wnt/beta-Catenin Signaling Pathway,Immunology & Inflammation,CD markers,Neuroscience,Calcium Signaling. Shipping: Ice Bag |
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Western blot analysis of various lysates usingCD324/E-Cadherin Rabbit pAb (A24874) at1:2000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Negative control (NC):HeLa. Exposure time:5s. |
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