Phospho-Axl-Y702 Rabbit mAb, Unconjugated
Artikelnummer:
ABB-AP1427
- Bilder (1)
| Artikelname: | Phospho-Axl-Y702 Rabbit mAb, Unconjugated |
| Artikelnummer: | ABB-AP1427 |
| Hersteller Artikelnummer: | AP1427 |
| Alternativnummer: | ABB-AP1427-500UL,ABB-AP1427-100UL,ABB-AP1427-1000UL,ABB-AP1427-20UL |
| Hersteller: | ABclonal |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | ELISA, WB |
| Spezies Reaktivität: | Human |
| Immunogen: | Synthetic peptide. This information is considered to be commercially sensitive. |
| Konjugation: | Unconjugated |
| Alternative Synonym: | ARK, UFO, JTK11, Tyro7, Phospho-Axl-Y702 |
| The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. The encoded protein acts as a host cell receptor for multiple viruses, including Marburg, Ebola and Lassa viruses and is a candidate receptor for the SARS-CoV2 virus. |
| Application Verdünnung: | WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. |
| Anwendungsbeschreibung: | Cross-Reactivity: Human. ResearchArea: Protein phosphorylation,Cancer,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology Developmental Biology,Cell Cycle,Immunology Inflammation. Shipping: Ice Bag |
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Western blot analysis of lysates from wild type (WT) and A-549 cells transfected with Gas6 using Phospho-Axl-Y702 Rabbit mAb (AP1427) at 1:500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 180s. |
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