Monoclonal Antibody to TLR8/CD288 FITC Conjugated (Clone: ABM15F6)
Artikelnummer:
ABI-10-3005-F-25
Hersteller Artikelnummer:
10-3005-F-25
Alternativnummer:
ABI-10-3005-F-25-25UG
Hersteller:
Abeomics
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
FACS
Spezies Reaktivität:
Human
Immunogen:
A partial length recombinant TLR8 protein (amino acids 750-900) was used as the immunogen for this antibody.
Konjugation:
FITC
Alternative Synonym:
TLR8||UNQ249/PRO286
Toll like receptor 8, also known as CD288, is a member of TLR family. It plays an important role in sensing phagocytosed pathogen. TLR8 recognizes ssRNA and recruits MyD88 and leads to the activation of transcription factor NF-kappa B. TLR8 TLR8 has two splice variants, viz., TLR8v1 and TLR8v2 and one missense variant, termed G or A1G allele of TLR8. TLR8v1 has additional 19 amino acids in the N-terminus. It is predominantly expressed in lung and peripheral blood leukocytes.
