A partial length recombinant DDX3 protein (amino acids 10-230) was used as the immunogen for this antibody.
Alternative Synonym:
DDX3X||DBX||DDX3
DDX3 (DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked) is having a large family of ATP-dependent RNA helicases that involve in several steps of RNA metabolism. Main functions of DDX3 involve transcription, mRNA export and translation, regulation of apoptosis and hepatitis C virus (HCV) replication. DDX3 has two isoforms produced by alternative splicing. The cytoplasmic form is highly phosphorylated in the G1/S. DDX3 is primarily expressed in nucleus during G0 phase and in the cytoplasm during G1/S phase.
Fig-1: Western blot analysis of DDX3. Anti- DDX3 antibody (Clone: ABM27H2) was used at 2 µg/ml on (1) MCF-7,(2) NIH3T3 (3) HEK293 and (4) EL-4 lysates.
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