Polyclonal Antibody to Cdc25B (Phospho-Ser149), Rabbit
Artikelnummer:
ABI-35-1333
Hersteller Artikelnummer:
35-1333
Alternativnummer:
ABI-35-1333-100UL
Hersteller:
Abeomics
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
WB
Spezies Reaktivität:
Mouse
Immunogen:
Peptide sequence around phosphorylation site of Serine 149 (F-R-S(p)-L-P) derived from Mouse Cdc25B.
Alternative Synonym:
CDC25B
Cdc25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist. Li G, et al. (2010) Retrovirology.7:59. Wang Z,et al. (2010) BMC Cancer.10:233. Lucci MA,et al. (2010) Cell Oncol.32(5-6):361-72.
Klonalität:
Polyclonal
UniProt:
Q9DB8
Formulierung:
Purified
Target-Kategorie:
Cdc25B (Phospho-Ser149)
Application Verdünnung:
Predicted MW: 62kd, Western blotting: 1:500~1:1000
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