Peptide sequence around aa.69~73 or 51~55 (T-P-T-P-T) derived from Human ATF2.
Alternative Synonym:
CREB2|| CREBP1
Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5-GTGACGT[AC][AG]-3), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2-c-Jun complex. Sevilla A, et al. (2004) J Biol Chem. 279(26):27458-27465. Waetzig G H, et al. (2002) J Immunol. 168(10): 5342-5351. Abdel-Hafiz H A, et al. (1992) Mol Endocrinol. 6: 2079-2089. Gupta S, et al. (1995) Science. 267: 389-393. Van Dam H, et al. (1995) EMBO J. 14(8): 1798-1811.
