Peptide sequence around aa. 392~396 (E-D-S-G-D) derived from Human HDAC2.
Alternative Synonym:
HD2|| Histone deacetylase 2
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes
