Peptide sequence around aa. 1~5 (M-A-S-G-V) derived from Human cofilin.
Alternative Synonym:
CFL|| CFL1|| COF1|| Cofilin
Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods. Kobayashi M, et al. (2006) EMBO J 25(4): 713-26. Wang Y, et al. (2005)Biol Chem 280(13): 12683-9. Smith-Beckerman DM, et al. (2005) Mol Cell Proteomics: 156-68.
