Polyclonal Antibody to AMPK Alpha1/AMPK Alpha2 (Ab-174/172), Rabbit
Artikelnummer:
ABI-35-1530
Hersteller Artikelnummer:
35-1530
Alternativnummer:
ABI-35-1530-100UL
Hersteller:
Abeomics
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
IF, IHC, WB
Spezies Reaktivität:
Human, Mouse, Rat
Immunogen:
Peptide sequence around aa. 172~176/170~174 (L-R-T-S-C) derived from Human AMPKa1/AMPKa2.
Alternative Synonym:
AMPK||AMPKa1
Responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. Appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5-AMP rises in response to fuel limitation and/or hypoxia. This is a catalytic subunit.
