Peptide sequence around aa.625~629 (V-E-Y-L-D) derived from Human Gab1.
Alternative Synonym:
Growth factor receptor bound protein 2-associated protein 1
The protein encoded by Gab1 is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Anders Kallin, et al. (2004) J. Biol. Chem, 279: 17897 - 17904. Hideto Kameda, et al. (2001) Cell Growth Differ, 12: 307. Masaki Osawa, et al. (2002) J. Cell Biol, 158: 773.
