Peptide sequence around aa.1344~1348 (Q-P-Y-A-H) derived from Human IGF-1R .
Alternative Synonym:
Insulin-like growth factor I receptor|| CD221|| IGF1R|| kinase IGF1R
This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1.
