Peptide sequence around aa. 408~412 ( T-S-T-F-C) derived from PKCz
Alternative Synonym:
PKC2|| PKC-ZETA|| PRKCZ
This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. Subunit of a quaternary complex that plays a central role in epithelial cell polarization.
