Peptide sequence around aa. 540~544 (H-E-Y-T-N) derived from Human SHP-2.
Alternative Synonym:
Protein-tyrosine phosphatase 2C
Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Ferjoux G, et al. (2003) Mol Biol Cell. 2003, 14(9): 3911-3928. Shi ZQ, et al. (2000) Mol Cell Biol , 20(5): 1526-1536. Li C, Friedman JM. (1999) Proc Natl Acad Sci U S A , 96(17): 9677-9682 Manes S, et al. (1999) Mol Cell Biol , 19(4): 3125-3135. Oh ES, et al. (1999) Mol Cell Biol, 19(4): 3205-3215.
