Peptide sequence around aa. 463~467 (C-S-S-M-S) derived from Human Smad2.
Alternative Synonym:
Mad-related protein 2
Transcriptional modulator activated by TGF-beta and activin type 1 receptor kinase. SMAD2 is a receptor-regulated SMAD (R-SMAD). May act as a tumor suppressor in colorectal carcinoma.
