Polyclonal Antibody to Melanoma-associated antigen D1, Rabbit
Artikelnummer:
ABI-35-1662
Hersteller Artikelnummer:
35-1662
Alternativnummer:
ABI-35-1662-100UL
Hersteller:
Abeomics
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
WB
Spezies Reaktivität:
Human, Mouse, Rat
Immunogen:
Peptide with sequence C-EAEARAEARNRMGIGDE derived from Mouse Melanoma-associated antigen D1.
Alternative Synonym:
MAGED1
Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Binds p75NTR and antagonizes its association with TrkA, inhibits cell cycle progression, and facilitates p75NTR-mediated apoptosis. May act as a regulator of the function of DLX family members. May regulate p53 transcriptional activity and inhibit cell proliferation. Enhances p53 phosphorylation and accumulation. Zhao Z,et al.(2002) Sci China C Life Sci.45(4):412-20. Shen WG,et al.(2007) Cell Commun Adhes.14(1):21-31. Cheresh DA,et al. (1984) J Biol Chem.259(12):7453-9.
