Peptide sequence around aa.569~573 (S-S-S-I-L) derived from Human BMAL1.
Alternative Synonym:
MOP3|| BMAL1c|| ARNTL|| TIC
ARNTL-CLOCK heterodimers activate E-box element (3-CACGTG-5) transcription of a number of proteins of the circadian clock. This transcription is inhibited in a feedback loop by PER, and also by CRY proteins Lee S,et al. (2010) PLoS One.5(6):e10995. Wang J,et al. (2010) Biosystems.101(2):136-43. Jung-Hynes ,et al. (2010) J Pineal Res.49(1):60-8.
