Peptide sequence around aa.41~45 (Y-V-Y-K-V) derived from Human H2B.
Alternative Synonym:
H2BQ|| GL105|| H2B.1|| H2BFQ|| H2BGL105
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
