Peptide sequence around aa.620~624(G-R-R-S-P) derived from Human ASH2L.
Alternative Synonym:
ASH2|| Bre2|| ASH2L1|| ASH2L2
Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates Lys-4 of histone H3, but not if the neighboring Lys-9 residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at Lys-4 of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis.
