Peptide sequence around aa.934~938 (H-I-Y-S-N) derived from Human c-Kit.
Alternative Synonym:
KIT, CD117, SCFR, PBT
This is the receptor for stem cell factor (mast cell growth factor). It has a tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase (Pi3K)
