Polyclonal Antibody to Doublecortin, Rabbit

Artikelnummer: ABI-35-1798
Artikelname: Polyclonal Antibody to Doublecortin, Rabbit
Artikelnummer: ABI-35-1798
Hersteller Artikelnummer: 35-1798
Alternativnummer: ABI-35-1798-100UL
Hersteller: Abeomics
Wirt: Rabbit
Kategorie: Antikörper
Applikation: WB
Spezies Reaktivität: Human, Mouse, Rat
Immunogen: Peptide sequence around aa.413~417( P-T-S-P-G) derived from Human Doublecortin.
Alternative Synonym: DCX|| DC|| DBCN
Seems to be required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCAMKL1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with LIS-1 of an overlapping, but distinct, signaling pathways that promote neuronal migration.
Klonalität: Polyclonal
NCBI: 1641
UniProt: O43602
Formulierung: Purified
Target-Kategorie: Doublecortin
Application Verdünnung: Predicted MW: 40-45kd, Western blotting: 1:500~1:1000