Peptide sequence around aa.289~293 (L-I-Y-D-F) derived from Human WASP.
Alternative Synonym:
THC|| THC1|| IMD2
Effector protein for Rho-type GTPases. Regulates actin filament reorganization via its interaction with the Arp2/3 complex. Important for efficient actin polymerization. Possible regulator of lymphocyte and platelet function. Mediates actin filament reorganization and the formation of actin pedestals upon infection by pathogenic bacteria.
