Monoclonal Antibody to CD100 (Semaphorin-4D)(Clone : 133-1C6), Clone: [133-1C6], Mouse
Artikelnummer:
ABI-36-1032
Hersteller Artikelnummer:
36-1032
Alternativnummer:
ABI-36-1032-100UG
Hersteller:
Abeomics
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
FACS, IF
Spezies Reaktivität:
Human
Immunogen:
PHA stimulated human peripheral blood lymphocytes.
Alternative Synonym:
SEMA4D||C9orf164||CD100||SEMAJ
Recognizes a homodimeric protein comprised of 50kDa subunits, identified as CD100 (Workshop VI, Code N-L026). It is expressed on majority of haemopoietic cells (B, T, NK and myeloid cells) and is absent from bone marrow, erythrocytes, eosinophils and endothelial cells. Its expression is increased after PHA-activation. CD100 was shown to associate with different partner molecules in T cells such as CD45, a key molecule with protein tyrosine phosphatase activity involved in T-cell transduction, and a Serine kinase. It plays a role in homotypic cell adhesion and in T cell activation.
