Monoclonal Antibody to CD100 (Semaphorin-4D)(Clone : A8), Mouse
Artikelnummer:
ABI-36-1033
Hersteller Artikelnummer:
36-1033
Alternativnummer:
ABI-36-1033-100UG
Hersteller:
Abeomics
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
FA, FACS, IF
Spezies Reaktivität:
Human, Mouse
Immunogen:
PHA stimulated human peripheral blood lymphocytes
Alternative Synonym:
SEMA4D||C9orf164||CD100||SEMAJ
Recognizes a homodimeric protein comprised of 50kDa subunits, identified as CD100. It is expressed on majority of haemopoietic cells (B, T, NK and myeloid cells) and is absent from bone marrow, erythrocytes, eosinophils and endothelial cells. Its expression is increased after PHA-activation. CD100 was shown to associate with different partner molecules in T cells such as CD45, a key molecule with protein tyrosine phosphatase activity involved in T-cell transduction, and a Serine kinase. It plays a role in homotypic cell adhesion and in T cell activation.
