Monoclonal Antibody to CD26 (DPP IV / ADA-Binding Protein)(Clone : 202.36), Clone: [202.36], Mouse
Artikelnummer:
ABI-36-1084
Hersteller Artikelnummer:
36-1084
Alternativnummer:
ABI-36-1084-100UG
Hersteller:
Abeomics
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
FACS, IF, IHC
Spezies Reaktivität:
Human, Rat
Immunogen:
Human T cell clone
Alternative Synonym:
DPP4||ADCP2||CD26
Recognizes a glycoprotein of 110kDa, identified as CD26 (Workshop VI, Code: N-L039). It is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and is upregulated during T-cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection. Cross-linking of CD26 using this antibody dramatically enhances the anti-CD3-induced IL-2 production. In Western blotting, this MAb reacts with only glycosylated CD26, but not with the deglycosylated form. It does not prevent ADA binding to CD26.
