Monoclonal Antibody to CD15 / FUT4 (Reed-Sternberg Cell Marker)(Clone : Leu-M1, same as MMA), Clone: [Leu-M1, same as MMA], Mouse
Artikelnummer:
ABI-36-1161
Hersteller Artikelnummer:
36-1161
Alternativnummer:
ABI-36-1161-100UG
Hersteller:
Abeomics
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
FACS, IF, IHC
Spezies Reaktivität:
Human
Immunogen:
U937 histiocytic cell line
Alternative Synonym:
FUT4||ELFT||FCT3A
CD15 plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. It is present on >95% of granulocytes including neutrophils and eosinophils and to a lesser degree on monocytes. In addition, CD15 is expressed in Reed-Sternberg cells and some epithelial cells. CD15 antibody is very useful in the identification of Hodgkin s disease. CD15 is occasionally expressed in large cell lymphomas of both B and T phenotypes which otherwise have a quite distinct histological appearance.
Flow Cytometry (1-2ug/million cells), Immunofluorescence (1-2ug/ml), Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min a
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