Monoclonal Antibody to Ku (p70/p80) (Nuclear Marker)(Clone : KU729), Clone: [KU729], Mouse
Artikelnummer:
ABI-36-1167
Hersteller Artikelnummer:
36-1167
Alternativnummer:
ABI-36-1167-100UG
Hersteller:
Abeomics
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
FACS, ICC, IF
Spezies Reaktivität:
Human
Immunogen:
Nuclear extract of human HL-60 cells
Alternative Synonym:
XRCC6||G22P1
Recognizes a dimer of two proteins of 70kDa and ~80kDa, identified as two subunits of Ku. This MAb recognizes a conformational epitope of p70/p80 dimer, which is destroyed during Western blotting. The p70/p80 dimer is important for function of a 460kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.
