Monoclonal Antibody to Blood Group Antigen H Type 2 (CD173)(Clone : 19-OLE), Clone: [19-OLE], Mouse
Artikelnummer:
ABI-36-1193
Hersteller Artikelnummer:
36-1193
Alternativnummer:
ABI-36-1193-100UG
Hersteller:
Abeomics
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
IF, IHC
Spezies Reaktivität:
Human
Immunogen:
Mucinous colonic adenocarcinoma
Alternative Synonym:
ABO
Recognizes the blood group H type 2 antigens, trisaccharide of human origin. This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity. It is expressed on endothelial cells, epithelial cells and granulocytes. Increased expression of this antigen has been observed on some tumor tissues such as gastric carcinomas, urothelial carcinomas, and colon carcinomas.
Immunofluorescence (2-4ug/ml), Immunohistology (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)
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