Monoclonal Antibody to IgM (Immunoglobulin Mu Heavy Chain) (B-Cell Marker)(IM260 + IM373 + ICO-30), Clone: [IM260 + IM373 + ICO-30], Mouse
Artikelnummer:
ABI-36-1282
Hersteller Artikelnummer:
36-1282
Alternativnummer:
ABI-36-1282-100UG
Hersteller:
Abeomics
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
IHC
Spezies Reaktivität:
Human
Immunogen:
Recombinant heavy chain of human IgM (IM260 & IM373), Heavy chain of human IgM (ICO-30)
Alternative Synonym:
IGHM
Recognizes a protein of 75kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
IgM (Immunoglobulin Mu Heavy Chain) (B-Cell Marker)
Application Verdünnung:
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95&degC followed by cooling at RT for 20 minutes),
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