Monoclonal Antibody to Smooth Muscle Myosin Heavy Chain (SM-MHC) (Leiomyosarcoma & Myoepithelial Cell Marker), Clone: [MYH11/923 + SMMS-1], Mouse

Artikelnummer: ABI-36-1487
Artikelname: Monoclonal Antibody to Smooth Muscle Myosin Heavy Chain (SM-MHC) (Leiomyosarcoma & Myoepithelial Cell Marker), Clone: [MYH11/923 + SMMS-1], Mouse
Artikelnummer: ABI-36-1487
Hersteller Artikelnummer: 36-1487
Alternativnummer: ABI-36-1487-100UG
Hersteller: Abeomics
Wirt: Mouse
Kategorie: Antikörper
Applikation: FACS, IF, IHC
Spezies Reaktivität: Human, Rat
Immunogen: Recombinant human MYH11 protein (MYH11/923), Human uterus extract (SMMS-1)
Alternative Synonym: MYH11||KIAA0866
Smooth muscle myosin heavy chain (SM-MHC) is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2. The antibody may be useful for the study of breast tumors as the presence of an intact layer of myoepithelial cells is an important feature, which may distinguish benign breast lesions and carcinoma in situ from invasive tumors.
Klonalität: Monoclonal
Klon-Bezeichnung: [MYH11/923 + SMMS-1]
NCBI: 4629
UniProt: P35749
Reinheit: Affinity Chromatography
Formulierung: Purified
Target-Kategorie: Smooth Muscle Myosin Heavy Chain (SM-MHC) (Leiomyosarcoma & Myoepithelial Cell Marker)
Application Verdünnung: Flow Cytometry (1-2ug/million cells), Immunofluorescence (1-2ug/ml), Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min a