Monoclonal Antibody to von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker)(Clone : VWF635), Clone: [VWF635], Mouse
Artikelnummer:
ABI-36-1804
Hersteller Artikelnummer:
36-1804
Alternativnummer:
ABI-36-1804-100UG
Hersteller:
Abeomics
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
FACS, IF, IHC, IP, WB
Spezies Reaktivität:
Human
Immunogen:
Recombinant human vWF fragment
Alternative Synonym:
VWF||F8VWF
von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposis sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.
von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker)
Application Verdünnung:
Immunoprecipitation (0.5-1 g/500ug protein lysate), Flow Cytometry (1-2ug/million cells), ,Immunofluorescence (1-2ug/ml), Western Blot (1-2ug/ml), ,Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues r
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