Monoclonal Antibody to Cdk1 / p34cdc2(Clone : POH-1, same as cdc2.1), Clone: [POH-1, same as cdc2.1], Mouse
Artikelnummer:
ABI-36-1985
Hersteller Artikelnummer:
36-1985
Alternativnummer:
ABI-36-1985-100UG
Hersteller:
Abeomics
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
IHC, WB
Spezies Reaktivität:
Human
Immunogen:
Purified recombinant human p34cdc2 fusion protein
Alternative Synonym:
CDK1||CDC2||CDC28A||CDKN1||P34CDC2
Recognizes a 34kDa protein, which is identified as cyclin dependent kinase 1 (cdk1) or p34cdc2 protein kinase. cdk1 / p34cdc2 plays a crucial role during cell division and is most active during mitosis. It is predominantly localized in the nucleus. It is a serine/threonine kinase, which is activated by cyclin, presumably by de-phosphorylation of tyrosine residues. Activated cdk1 / p34cdc2 performs specific functions during mitosis, including nuclear envelope breakdown and chromosome condensation.
Western Blot (1-2ug/ml),Immunohistochemistry (Formalin-fixed) (2-4ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95&degC followed by cooling at RT for 2
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