Anti-Chromogranin A / CHGA (Neuroendocrine Marker) Polyclonal Antibody, Rabbit
Artikelnummer:
ABI-36-2081
Hersteller Artikelnummer:
36-2081
Alternativnummer:
ABI-36-2081-100UG
Hersteller:
Abeomics
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
ELISA, FACS, IF, IHC
Spezies Reaktivität:
Human
Immunogen:
Recombinant human chromogranin A protein
Alternative Synonym:
Beta-Granin, CGA, CHGA, Chromogranin A Parathyroid Secretory Protein 1, ER-37, Pancreastatin, Parastatin, Parathyroid Secretory Protein 1, Pituitary Secretory Protein I, SP-I, Vasostatin I or II
Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
ELISA (For coating use Ab at 1-5ug/ml, order Ab without BSA),,Flow Cytometry (1-2ug/million cells), ,Immunofluorescence (1-2ug/ml). ,Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating
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