Anti-Collagen VII Monoclonal Antibody(Clone: LH7.2), Clone: [LH7.2], Mouse
Artikelnummer:
ABI-36-2106-20
Hersteller Artikelnummer:
36-2106-20
Alternativnummer:
ABI-36-2106-20-20UG
Hersteller:
Abeomics
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
ELISA, FACS, IF, IHC, WB
Spezies Reaktivität:
Human
Immunogen:
Recombinant full-length human Collagen VII protein
Alternative Synonym:
Alpha 1 type VII collagen, Collagen 7, Collagen alpha 1(VII) chain, Collagen type VII alpha 1, Collagen VII alpha 1 polypeptide Col7a1, EBD1, EBDCT, EBR1, Long-chain (LC) collagen
Recognizes an epitope located on collagenase digested Type VII collagen (150kDa), i.e. the non-helical carboxyl terminal region of the dimer. Binding is localized at the inferior border of the lamina densa as demonstrated by immunoelectron microscopy. Type VII is also found in the retina, where its function is unknown. It interacts with Laminin 5 and Fibronectin. Collagen VII is a stratified squamous epithelial basement membrane protein that forms anchoring fibrils which may contribute to epithelial basement membrane organization and adherence by interacting with extracellular matrix (ECM) proteins such as type IV collagen.
ELISA (For coating, order antibody without BSA), Western Blot (1-2ug/ml)Flow Cytometry (1-2ug/million cells), Immunofluorescence (1-2ug/ml), Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires
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