Anti-CD15 / FUT4 (Reed-Sternberg Cell Marker) Monoclonal Antibody(Clone: SPM119), Clone: [SPM119], Mouse

Artikelnummer: ABI-36-2354-20
Artikelname: Anti-CD15 / FUT4 (Reed-Sternberg Cell Marker) Monoclonal Antibody(Clone: SPM119), Clone: [SPM119], Mouse
Artikelnummer: ABI-36-2354-20
Hersteller Artikelnummer: 36-2354-20
Alternativnummer: ABI-36-2354-20-20UG
Hersteller: Abeomics
Wirt: Mouse
Kategorie: Antikörper
Applikation: FACS, IF, IHC
Spezies Reaktivität: Human
Immunogen: U937 histiocytic cell line
Alternative Synonym: 3 Fucosyl N Acetyl Lactosamine, Alpha (1,3) Fucosyltransferase, Alpha 13 fucosyltransferase FucT, ELAM Ligand Fucosyltransferase, ELFT, FCT3A, Fuc-TIV, Fucosyltransferase 4 Alpha 1 3 Fucosyltransferase Myeloid Specific, Fucosyltransferase 4, Galactoside 3 L Fucosyltransferase, Lewis X, LeX, SSEA1, S
CD15 plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. It is present on 95% of granulocytes including neutrophils and eosinophils and to a lesser degree on monocytes. In addition, CD15 is expressed in Reed-Sternberg cells and some epithelial cells. CD15 antibody is very useful in the identification of Hodgkin s disease. CD15 is occasionally expressed in large cell lymphomas of both B and T phenotypes which otherwise have a quite distinct histological appearance.
Klonalität: Monoclonal
Klon-Bezeichnung: [SPM119]
NCBI: 2526
UniProt: P22083
Application Verdünnung: Flow Cytometry (1-2ug/million cells), Immunofluorescence (1-2ug/ml), ,Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 1mM EDTA, pH 7.5-8.5, for 45 min at 95&