Recombinant fragment of human TACSTD2 protein (around aa 31-274) (exact sequence is proprietary)
Alternative Synonym:
Cell surface glycoprotein Trop-2,Membrane Component Chromosome 1, Surface Marker 1 (M1S1),Pancreatic Carcinoma Marker Protein GA733-1,TROP2,Tumor-Associated Calcium Signal Transducer 2 (TACSTD2)
TACSTD2is a cell surface glycoprotein receptor. It is a single pass type I membrane protein containing one thyroglobulin type-1 domain, an epidermal growth factor-like repeat, a phosphatidylinositol binding site and tyrosine phosphorylation sites near the C-terminus. It plays a role intransducing intracellular calcium signals. It is expressed in trophoblast cells, cornea and multi-stratified epithelia. It is also highly expressed in several types of tumors and is involved in regulating the growth of carcinoma cells.
Western Blot (1-2ug/ml), ,Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 &degC followed by cooling at RT f
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