Anti-MMP2 / Collagenase Type IV A (Tumor Metastasis Marker) Monoclonal Antibody(Clone: MMP2/1501), Clone: [MMP2/1501], Mouse
Artikelnummer:
ABI-36-2787
Hersteller Artikelnummer:
36-2787
Alternativnummer:
ABI-36-2787-100UG
Hersteller:
Abeomics
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
WB
Spezies Reaktivität:
Human
Immunogen:
Recombinant human MMP2 protein fragment (aa 444-575) (exact sequence is proprietary)
Alternative Synonym:
72kD type IV collagenase, CLG4A, Collagenase Type 4 alpha, Collagenase type IV A, Gelatinase A, Gelatinase alpha, Gelatinase neutrophil, Matrix metalloproteinase-2, MMP2, MONA, Neutrophil gelatinase, PEX, TBE-1
It recognizes a protein of 72kDa, which is identified as MMP2. The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-2 (also designated type IV collagenase) cleaves collagen types IV,V, VII and X and gelatin type I. Activation of MMP-2 secretion requires the Ras signaling pathway.
