Recombinant human Alpha-1-Antitrypsin (AAT) protein fragment
Alternative Synonym:
A1AT, Alpha-1 protease inhibitor, Alpha-1-antiproteinase (Alpha1AT), Dom1, Serine (or cysteine) proteinase inhibitor clade A member 1, Serpin peptidase inhibitor clade A member 1, Short peptide from AAT (SPAAT), Spi1-1
It recognizes a protein of 54kDa, which is identified antitrypsin (AAT). The immunohistochemical staining of AAT is useful in identification of benign and malignant hepatic tumors and yolk sac carcinomas. Positive staining for AAT is also used in detection of benign and malignant lesions of histiocytic nature. This antibody is may also useful tool in the screening of patients with cryptogenic cirrhosis or other forms of liver disease with fibrosis of uncertain origin.
Western Blot (1-2ug/ml), Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95&degC followed by cooling at RT for
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