Anti-Replication Protein A2 (RPA2) Monoclonal Antibody(Clone: RPA2/2106), Clone: [RPA2/2106], Mouse
Artikelnummer:
ABI-36-3115
Hersteller Artikelnummer:
36-3115
Alternativnummer:
ABI-36-3115-100UG
Hersteller:
Abeomics
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
WB
Spezies Reaktivität:
Human
Immunogen:
Recombinant human full-length Replication protein A2 (RPA2) protein
Alternative Synonym:
p32, p34, REPA2, Replication protein A 32kDa subunit, Replication protein A 34kDa subunit, Replication protein A2, RF-A protein 2, Rf-A2, RFA, RP-A p32, RP-A p34, RP21C, RPA32, RPA34, RpLP1, RpP2
Recognizes a protein of 34kDa, identified as a subunit of Replication Protein A (RPA) (also known as human single-stranded DNA binding protein, or HSSB). RPA from human cells is a stable heterotrimer of 70kDa, 32-34kDa, and 11-14kDa subunits (RPA70, RPA32, and RPA14 respectively). It is involved in DNA replication, repair, and recombination. RPA is required for the SV40 large tumor antigen-catalyzed unwinding of SV40 DNA and stimulates DNA polymerase (pol) alpha and delta. RPA34 is phosphorylated at the G1/S boundary of the cell cycle or upon exposure of cells to DNA damage-inducing agents including ionizing and UV radiation.
