Biotinylated Human CNTF R alpha Protein, His,Avitag(TM)
Artikelnummer:
ABS-CNR-H82Q3-25UG
Hersteller Artikelnummer:
CNR-H82Q3-25ug
Alternativnummer:
ABS-CNR-H82Q3-25UG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Konjugation:
Biotin
CNTF receptor alpha (CNTFR) is a specialized protein primarily expressed in the nervous system and skeletal muscle. Unlike many receptors, it lacks a transmembrane domain and anchors to the cell surface via a GPI linkage. It functions as a crucial signaling component that binds Ciliary Neurotrophic Factor, subsequently recruiting gp130 and LIFR to initiate the JAK/STAT pathway. This process is vital for promoting neuronal survival, guiding motor neuron development, and regulating muscle regeneration. - Proteine/Peptide