PGP9.5 / UchL1 (pan-Neuronal Marker) Antibody - With BSA and Azide, Clone: [SPM575], Mouse, Monoclonal
Artikelnummer:
ABT-AH10804-U0100
- Bilder (0)
| Artikelname: | PGP9.5 / UchL1 (pan-Neuronal Marker) Antibody - With BSA and Azide, Clone: [SPM575], Mouse, Monoclonal |
| Artikelnummer: | ABT-AH10804-U0100 |
| Hersteller Artikelnummer: | AH10804-U0100 |
| Alternativnummer: | ABT-AH10804-U0100-100UG |
| Hersteller: | Abcepta |
| Wirt: | Mouse |
| Kategorie: | Antikörper |
| Applikation: | IF, WB |
| Spezies Reaktivität: | Guinea pig, Human, Mouse, Porcine, Rabbit, Rat, Zebrafish |
| Alternative Synonym: | Ubiquitin carboxyl-terminal hydrolase isozyme L1, UCH-L1, 3.4.19.12, 6.-.-.-, Neuron cytoplasmic protein 9.5, PGP 9.5, PGP9.5, Ubiquitin thioesterase L1, UCHL1 |
| This MAb reacts with a protein of 20-30kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinsons disease. |
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