CD100 (Semaphorin-4D) Antibody - With BSA and Azide, Clone: [133-1C6], Mouse, Monoclonal
Artikelnummer:
ABT-AH11057-U0020
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| Artikelname: | CD100 (Semaphorin-4D) Antibody - With BSA and Azide, Clone: [133-1C6], Mouse, Monoclonal |
| Artikelnummer: | ABT-AH11057-U0020 |
| Hersteller Artikelnummer: | AH11057-U0020 |
| Alternativnummer: | ABT-AH11057-U0020-20UG |
| Hersteller: | Abcepta |
| Wirt: | Mouse |
| Kategorie: | Antikörper |
| Applikation: | FC, IF |
| Spezies Reaktivität: | Human, Primate |
| Alternative Synonym: | Semaphorin-4D, A8, BB18, GR3, CD100, SEMA4D, C9orf164, CD100, SEMAJ |
| Recognizes a homodimeric protein comprised of 50kDa subunits, identified as CD100 (Workshop VI, Code N-L026). It is expressed on majority of haemopoietic cells (B, T, NK and myeloid cells) and is absent from bone marrow, erythrocytes, eosinophils and endothelial cells. Its expression is increased after PHA-activation. CD100 was shown to associate with different partner molecules in T cells such as CD45, a key molecule with protein tyrosine phosphatase activity involved in T-cell transduction, and a Serine kinase. It plays a role in homotypic cell adhesion and in T cell activation. |
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